THERAPEUTIC EFFICACY OF RIFAMPICIN AGAINST TRICHINELLA SPIRALIS IN MICE
نویسندگان
چکیده
منابع مشابه
Efficacy of mebendazole and albendazole against Trichinella spiralis in mice.
Changes in the sensitivity of Trichinella spiralis to anthelmintic treatment during the first 3 days of infection in mice were studied. Oral administration of either mebendazole or albendazole at 6.25 mh/kg 2 hr after exposure to infection eliminated 95-100% of the worms as determined at necropsy on day 7 postinoculation. Beyond the first day of infection the sensitivity of the parasite to benz...
متن کاملThe efficacy of flubendazole against Trichinella spiralis in swine.
A trial was undertaken to assess the efficacy of flubendazole against experimentally induced trichinellosis in pigs when given mixed with food at different dose rates. At the start of the experiment, 48 pigs were infected with approximately 35,000 larvae of Trichinella spiralis, afterwards the animals were distributed in six groups. The first three groups were used to test the activity of the d...
متن کاملTherapeutic efficacy of Dormectin, Ivermectin and Levamisole against different stages of Trichinella spiralis in rats.
OBJECTIVE Three commonly used antihelmenthic drugs including Dormectin (0.2 mg/kg), Ivermectin (0.2 mg/kg) and Levamisole (7.5 mg/kg) were examined for their antihelmenthic efficacy against experimental Trichinella spiralis infection in rats. METHODS One hundred and twenty rats were orally infected with 500 T. spiralis larvae. Drugs were tested against adult worms at 4th day, against migratin...
متن کاملTherapeutic Potential of Myrrh and Ivermectin against Experimental Trichinella spiralis Infection in Mice
Trichinosis is a parasitic zoonosis caused by the nematode Trichinella spiralis. Anthelmintics are used to eliminate intestinal adults as well as tissue-migrating and encysted larvae. This study aimed to investigate the effects of ivermectin and myrrh obtained from the aloe-gum resin of Commiphora molmol on experimental trichinosis. Ninety albino mice were orally infected with 300 T. spiralis l...
متن کاملEfficacy of albendazole against early and late stage of Trichinella spiralis infection in mice.
Efficacy of albendazole against early and late stage of Trichinella spiralis infection in mice was determined. To determine the efficacy of albendazole against the early stage (enteral phase) of trichinosis, mice experimentally infected with T. spiralis were treated with albendazole 20 mg/kg at 7 days post infection for 15 days. Larvae were recovered from the infected mice 7 days after the trea...
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ژورنال
عنوان ژورنال: Journal of the Egyptian Society of Parasitology
سال: 2023
ISSN: ['2090-2549', '1110-0583']
DOI: https://doi.org/10.21608/jesp.2023.312174